Fleas and ticks are not just a nuisance, they're also a real threat to your pet's health. Dogs and cats not treated with flea and tick medication, either in the form of a topical treatment or a flea and tick pill, can suffer everything from flea allergy dermatitis (which causes your animal to bite and scratch himself and sometimes lose his hair) to tapeworms.
Since a single female flea can produce up to 2,000 eggs in her three-week lifespan, a dog can become infested quickly. Tick bites are even more dangerous. A single tick bite can transmit Lyme disease, Rocky Mountain spotted fever, tularemia, ehrlichiosis and other diseases. Signs and symptoms of tick-borne illnesses may take anywhere from 7 to 21 or more days to appear, according to the Centers for Disease Control.
Luckily, there are many types of flea and tick medications available to stop these tiny terrors from making their home on your dog or cat. The most popular kind of effective treatment is a topical medication generally applied once a month. A newer preventive measure is a flea and tick pill. Are you curious about which of the two methods might work best for your pet? Here's a look at the pros and cons of each type of treatment.
Oral Treatments

Oral flea and tick medication treatments—which come as chewables or pills — are ingested by your pet, rather than applied to his body. The medicine is transmitted to adult fleas when they bite your pet. There are different active chemicals used in different flea and tick pill medications, some of which last a few days and others that last a month. The most common active chemicals in oral treatments include:
- Lufenuron: This compound does not kill adult fleas. Instead, any larvae produced by the adults will not survive. Medications with this chemical are approved by the Federal Drug Administration (FDA) for dogs and cats. It does not kill ticks.
- Spinosad: Spinosad only kills adult fleas, not ticks. It works by overstimulating the flea's nervous system, which causes its death. Medicines with spinosad are not recommended for dogs with epilepsy. Harvard Medical School also reports that the FDA approved a topical medication called Natroba for humans as a head lice treatment. The active chemical in Natroba? Spinosad.
- Nitenpyram: This fast-acting insecticide kills adult fleas in as little as thirty minutes. It doesn't have long-term effect, so it shouldn't be used for continuous flea control. Instead, it might be an option if you are planning a short-term trip to an area where you expect fleas will be present, such as a boarding kennel or a dog park. It is worth noting that most vets use this to kill fleas quickly, rather than use it as a preventative solution. It is approved for use by the FDA in cats and dogs, and it also kills ticks.
Topical Treatments
Topical flea and tick medication, also called "spot on" medications, are generally applied between the pet's shoulder blades so the pet can't lick it off. Most topical medications last a month. Some topical medications not only kill fleas and ticks, they also repel them. The most common active chemicals in topical medications are:
- Fipronil: Fipronil works by attacking the nervous system of the parasite to paralyze fleas and ticks to ultimately kill them. Fipronil spreads over the cat or dog through body oils in about a day. It releases over time — usually about a month. It is approved by the Environmental Protection Agency (EPA) for use on cats and dogs.
- Imidacloprid: This ingredient kills fleas by disrupting the nervous system. It kills both adult and larval stage fleas that come in contact with the pet. It is approved by the EPA for use on cats and dogs.
- Pyrethroids: You may see pyrethroids on the list of active ingredients under a few different names. It is an organic compound derived from a flower, which makes it popular among pet owners who prefer all-natural products, though there are also synthetic pyrethroids that some manufacturers prefer because they are more stable and last longer. Pyrethroids are not approved for use on cats by the EPA, and should be used with caution on small dogs, and never in households with cats as it is extremely toxic to felines. Products with pyrethroids kill fleas, ticks and mites.